卡贝缩宫素在剖宫产术中的应用效果(1)
[摘要]目的 探讨卡贝缩宫素在剖宫产术中的应用效果。方法 选取2018年1～12月我院收治的100例行剖宫产的产妇作为研究对象，根据随机数字表法分为研究组(50例)与对照组(50例)。对照组产妇应用缩宫素，研究组产妇应用卡贝缩宫素。比较分析两组产妇的出血量情况、间接出血指标以及药物不良反应发生情况。结果 研究组产妇的术中出血量、术后2、24 h出血量均低于对照组，差异有统计学意义(P<0.05);研究组产妇的血红蛋白、红细胞比容、收缩压、舒张压水平均高于对照组，差异有统计学意义(P<0.05);研究组产妇的心率低于对照组，差异有统计学意义(P<0.05);研究组的不良反应总发生率低于对照组，差异有统计学意义(P<0.05)。结论 在剖宫产术中，给予产妇卡贝缩宫素预防产后出血的效果确切，安全性高，值得推广。
[关键词]剖宫产术;卡贝缩宫素;预防;产后出血
[中图分类号] R719.8 [文献标识码] A [文章编号] 1674-4721(2019)9(b)-0107-03
Application effect of Carbetocin in cesarean section
DING Jiang-ling
Department of Obstetrics and Gynecology， Jingdezhen Second People′s Hospital， Jiangxi Province， Jingdezhen 333000， China
[Abstract] Objective To investigate the effect of Carbetocin in cesarean section. Methods A total of 100 women undergoing cesarean section from January to December 2018 were selected as the subjects. They were divided into study group (50 cases) and control group (50 cases) according to the random number table method. The control group was treated with Oxytocin， and the study group was treated with Carbetocin. The blood loss， indirect bleeding， and adverse drug reactions were compared. Results The intraoperative bleeding volume， 2 h postoperatively bleeding volume， 24 h postoperatively bleeding volume in the study group were lower than those in the control group， and the differences were statistically significant (P<0.05). The hemoglobin， hematocrit， systolic blood pressure， diastolic blood pressure in the study group were higher than those in the control group， and the differences were statistically significant (P<0.05). The heart rate of the study group was lower than that of the control group， and the difference was statistically significant (P<0.05). The total incidence rate of adverse reactions in the study group was lower than that in the control group， and the difference was statistically significant (P<0.05). Conclusion In cesarean section， the application of Carbetocin in the treatment of postpartum hemorrhage is effective and safe， which is worth popularizing.
[Key words] Cesarean section; Carbetocin; Prevention; Postpartum hemorrhage
隨着近年来临床妇产科产妇剖宫产率的逐渐增多，剖宫产已经成为临床常见的产妇分娩方式。但是，剖宫产属于创伤性分娩方式，且容易致使产后出血，威胁产妇及胎儿的生命安全[1-2]。产后出血为临床常见的分娩后并发症类型之一，主要是指阴道分娩的产妇娩出胎儿后24 h内，出血量≥500 ml，剖宫产的产妇娩出胎儿后24 h内，出血量≥1000 ml[3-4]。相关临床数据统计显示，剖宫产发生产后出血的概率为5.00%～10.00%[5]。但由于临床上估计的产后出血量往往比实际出血量低，因此产后出血的实际发生率更高。临床需加强有效的干预措施，以预防或积极治疗产后出血，从而避免产妇及其胎儿受到生命威胁[6-7]。本研究选取100例于我院行剖宫产的产妇作为研究对象，旨在探讨卡贝缩宫素在剖宫产术中的应用效果，现报道如下。, 百拇医药(丁江玲)
[关键词]剖宫产术;卡贝缩宫素;预防;产后出血
[中图分类号] R719.8 [文献标识码] A [文章编号] 1674-4721(2019)9(b)-0107-03
Application effect of Carbetocin in cesarean section
DING Jiang-ling
Department of Obstetrics and Gynecology， Jingdezhen Second People′s Hospital， Jiangxi Province， Jingdezhen 333000， China
[Abstract] Objective To investigate the effect of Carbetocin in cesarean section. Methods A total of 100 women undergoing cesarean section from January to December 2018 were selected as the subjects. They were divided into study group (50 cases) and control group (50 cases) according to the random number table method. The control group was treated with Oxytocin， and the study group was treated with Carbetocin. The blood loss， indirect bleeding， and adverse drug reactions were compared. Results The intraoperative bleeding volume， 2 h postoperatively bleeding volume， 24 h postoperatively bleeding volume in the study group were lower than those in the control group， and the differences were statistically significant (P<0.05). The hemoglobin， hematocrit， systolic blood pressure， diastolic blood pressure in the study group were higher than those in the control group， and the differences were statistically significant (P<0.05). The heart rate of the study group was lower than that of the control group， and the difference was statistically significant (P<0.05). The total incidence rate of adverse reactions in the study group was lower than that in the control group， and the difference was statistically significant (P<0.05). Conclusion In cesarean section， the application of Carbetocin in the treatment of postpartum hemorrhage is effective and safe， which is worth popularizing.
[Key words] Cesarean section; Carbetocin; Prevention; Postpartum hemorrhage
隨着近年来临床妇产科产妇剖宫产率的逐渐增多，剖宫产已经成为临床常见的产妇分娩方式。但是，剖宫产属于创伤性分娩方式，且容易致使产后出血，威胁产妇及胎儿的生命安全[1-2]。产后出血为临床常见的分娩后并发症类型之一，主要是指阴道分娩的产妇娩出胎儿后24 h内，出血量≥500 ml，剖宫产的产妇娩出胎儿后24 h内，出血量≥1000 ml[3-4]。相关临床数据统计显示，剖宫产发生产后出血的概率为5.00%～10.00%[5]。但由于临床上估计的产后出血量往往比实际出血量低，因此产后出血的实际发生率更高。临床需加强有效的干预措施，以预防或积极治疗产后出血，从而避免产妇及其胎儿受到生命威胁[6-7]。本研究选取100例于我院行剖宫产的产妇作为研究对象，旨在探讨卡贝缩宫素在剖宫产术中的应用效果，现报道如下。, 百拇医药(丁江玲)