【摘要】 目的 探讨膀胱癌的预后和环氧化酶-2的关系。方法 分析56例膀胱癌术后患者临床资料， 通过免疫组化的方法对环氧化酶-2阳性率进行判定。结果 膀胱癌不同病理分级和环氧化酶-2阳性率呈现明显的正相关， 膀胱癌淋巴结转移和环氧化酶-2阳性率呈现明显的正相关(P<0.05)。结论 环氧化酶-2和膀胱癌的发生、发展、预后有着密切的联系， 为指导临床合理用药提供了可靠的理论依据。

    【关键词】 膀胱癌；预后；环氧化酶-2；关系

    DOI：10.14163/j.cnki.11-5547/r.2015.21.003

    【Abstract】 Objective To investigate relationship between prognosis of bladder cancer and cyclooxygenase-2. Methods Clinical data of 56 bladder cancer patients were analyzed after operation. Immunohistochemical method was applied to detect positive rate of cyclooxygenase-2. Results There was a obviously positive correlation between pathological classification of bladder cancer and positive rate of cyclooxygenase-2. Lymphatic metastasis of bladder cancer also had positive correlation with positive rate of cyclooxygenase-2 (P<0.05). Conclusion Cyclooxygenase-2 is closely related with occurrence ......